I'm a math geek, so I enjoy reading the occasional comic strip that's math related. Here is my list of the top 10 webcomics/comics that I read on a regular basis:
1.
Foxtrot - Surely, everyone knows this one. It occasionally has a lot of math humor but is currently on a Sunday only publication schedule.
2.
xkcd - Updated every Mon, Wed, Fri, and a very popular webcomic online.
3.
Abstruse Goose - Funny webcomic updated regularly, but often physics related as well.
4.
Spiked Math - New daily webcomic in color.